EPIDEMIOLOGICAL EVALUATION AND ANALYSIS OF CLINICAL AND BIOCHEMICAL CHANGES IN COWS WITH ABOMASAL DISPLACEMENT
Abomasum, dairy cow, liver function, kidney function, clinical signs.
The displacement of the abomasum (DA) in dairy cattle is a multifactorial gastrointestinal disorder with significant economic and animal welfare impacts, predominantly affecting high-producing cows during the transition period, three weeks before and after calving. DA can occur as left displacement (LDA) or right displacement (RDA), with LDA being more frequent and RDA associated with greater severity, potentially progressing to abomasal volvulus (AV). Clinically, affected cows present anorexia, reduced milk yield, apathy,
ruminal stasis, abdominal distension, and melena, with more severe cases exhibiting tachycardia, dehydration, and shock. The disease is closely linked to metabolic imbalances, particularly negative energy balance, hepatic lipidosis, and ketosis, which compromise abomasal motility and contribute to gas accumulation. Nutritional factors, such as diets high in soluble carbohydrates and low in fiber, along with hormonal, anatomical, and
immunological changes during the peripartum period, exacerbate the risk. Laboratory analyses provide crucial insights into disease severity and prognosis: serum protein profiles reveal hypoalbuminemia, hyperglobulinemia, and altered albumin/globulin ratios, indicating impaired hepatic function and systemic inflammatory response; hepatic enzymes, including AST and GGT, reflect hepatocellular and biliary compromise; renal biomarkers, such as creatinine and urea, highlight prerenal dysfunction due to dehydration and hypoperfusion, particularly in AV cases. Epidemiologically, DA is most prevalent within the first month postpartum, especially in Holstein and crossbred dairy cows, with incidence influenced by genetic potential, diet, environmental conditions, and management practices. The integration of clinical, biochemical, and epidemiological data enables early detection, guides therapeutic interventions—ranging from conservative management to surgical correction—and improves
prognosis, emphasizing the importance of preventive strategies, nutritional optimization, and metabolic monitoring to mitigate the impact of DA in high-producing dairy herds.